产品详情
简单介绍:
Human NTSR1 (Neurotensin Receptor 1, High Affinity) Sandwich ELISA Kit Ready-To-Use (STJE0017519)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.126ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This NTSR1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | NTSR1 |
Gene ID: | 4923 |
Uniprot ID: | NTR1_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain. |
Post Translational Modifications | N-glycosylated. Palmitoylated.this is required for normal localization at membrane rafts and normal GNA11-mediated activation of down-stream signaling cascades. The palmitoylation level increases in response to neurotensin treatment. |
Function | G-protein coupled receptor for the tridecapeptide neurotensin (NTS). Signaling is effected via G proteins that activate a phosphatidylinositol-calcium second messenger system. Signaling leads to the activation of downstream MAP kinases and protects cells against apoptosis. |
Protein Name | Neurotensin Receptor Type 1 Nt-R-1 Ntr1 High-Affinity Levocabastine-Insensitive Neurotensin Receptor Ntrh |
Database Links | Reactome: R-HSA-375276 Reactome: R-HSA-416476 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Membrane Raft Palmitoylation Is Required For Localization At Cav1-Enriched Membrane Rafts |
Alternative ELISA Names | Neurotensin Receptor Type 1 ELISA kit Nt-R-1 ELISA kit Ntr1 ELISA kit High-Affinity Levocabastine-Insensitive Neurotensin Receptor ELISA kit Ntrh ELISA kit NTSR1 ELISA kit NTRR ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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