产品详情
简单介绍:
Anti-CDKN1C antibody [KP10] (STJ180208)
详情介绍:
Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-CDKN1C is suitable for use in Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | KP10 |
Conjugation: | Unconjugated |
Isotype: | IgG2b/Kappa |
Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% proclin<="" td=""> 0.1%> |
Purification: | Affinity purified |
Dilution Range: | 1:100‐500 |
Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
Gene Symbol: | CDKN1C |
Gene ID: | 1028 |
Uniprot ID: | CDN1C_HUMAN |
Specificity: | Positive control: Colon carcinoma or placenta |
Immunogen: | Recombinant human p57Kip2 protein |
Tissue Specificity | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. |
Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. |
Protein Name | Cyclin-Dependent Kinase Inhibitor 1c Cyclin-Dependent Kinase Inhibitor P57 P57kip2 |
Database Links | Reactome: R-HSA-69231 Reactome: R-HSA-9661069 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Cyclin-Dependent Kinase Inhibitor 1c antibody Anti-Cyclin-Dependent Kinase Inhibitor P57 antibody Anti-P57kip2 antibody Anti-CDKN1C antibody Anti-KIP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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