產品詳情
簡單介紹：
Anti-FBXO32 antibody (206-355) (STJ28908)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FBXO32 (206-355) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FBXO32 |
| Gene ID: | 114907 |
| Uniprot ID: | FBX32_HUMAN |
| Immunogen Region: | 206-355 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBOX32 (NP_478136.1). |
| Immunogen Sequence: | WQQQLNNIQITRPAFKGLTF TDLPLCLQLNIMQRLSDGRD LVSLGQAAPDLHVLSEDRLL WKKLCQYHFSERQIRKRLIL SDKGQLDWKKMYFKLVRCYP RKEQYGDTLQLCKHCHILSW KGTDHPCTANNPESCSVSLS PQDFINLFKF |
| Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
| Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
| Protein Name | F-Box Only Protein 32 Atrogin-1 Muscle Atrophy F-Box Protein Mafbx |
| Database Links | Reactome: R-HSA-8951664 Reactome: R-HSA-9615017 Reactome: R-HSA-983168 |
| Cellular Localisation | Cytoplasm Nucleus Shuttles Between Cytoplasm And The Nucleus |
| Alternative Antibody Names | Anti-F-Box Only Protein 32 antibody Anti-Atrogin-1 antibody Anti-Muscle Atrophy F-Box Protein antibody Anti-Mafbx antibody Anti-FBXO32 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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