产品详情

  • 产品名称：Anti-CDCA7L antibody (1-300) (STJ117667)

  • 产品型号：STJ117667
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CDCA7L antibody (1-300) (STJ117667)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDCA7L (1-300) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDCA7L
Gene ID: 55536
Uniprot ID: CDA7L_HUMAN
Immunogen Region: 1-300
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human CDCA7L (NP_061189.2).
Immunogen Sequence: MELATRYQIPKEVADIFNAP SDDEEFVGFRDDVPMETLSS EESCDSFDSLESGKQQDVRF HSKYFTEELRRIFIEDTDSE TEDFAGFTQSDLNGKTNPEV MVVESDLSDDGKASLVSEEE EDEEEDKATPRRSRSRRSSI GLRVAFQFPTKKLANKPDKN SSSEQLFSSARLQNEKKTIL ERKKDCRQVIQREDSTSESE DDSRDESQESSDALLKRTMN IKENKAMLAQLLAELNSMP
Tissue Specificity Ubiquitous. Overexpressed in medulloblastoma.
Post Translational Modifications Phosphorylation increases its interaction with PSIP1.
Function Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways.May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Protein Name Cell Division Cycle-Associated 7-Like Protein
Protein Jpo2
Transcription Factor Ram2
Cellular Localisation Cytoplasm
Nucleus
Associates With Chromatin
Translocates From Cytoplasm To Nucleus Under Dexamethasone Induction
Alternative Antibody Names Anti-Cell Division Cycle-Associated 7-Like Protein antibody
Anti-Protein Jpo2 antibody
Anti-Transcription Factor Ram2 antibody
Anti-CDCA7L antibody
Anti-HR1 antibody
Anti-JPO2 antibody
Anti-R1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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