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Anti-CYP39A1 antibody (Internal) (STJ92592) STJ92592|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情
  • 產品名稱:Anti-CYP39A1 antibody (Internal) (STJ92592)

  • 產品型號:STJ92592
  • 產品廠商:ST john's laboratory
  • 產品文檔:
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簡單介紹:
Anti-CYP39A1 antibody (Internal) (STJ92592)
詳情介紹:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-24-hydroxycholesterol 7-alpha-hydroxylase (Internal) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CYP39A1
Gene ID: 51302
Uniprot ID: CP39A_HUMAN
Immunogen Region: Internal
Specificity: CYP39A1 Polyclonal Antibody detects endogenous levels of CYP39A1 protein.
Immunogen: Synthesized peptide derived from the Internal region of human CYP39A1.
Function A cytochrome P450 monooxygenase involved in neural cholesterol clearance through bile acid synthesis. Catalyzes 7-alpha hydroxylation of (24S)-hydroxycholesterol, a neural oxysterol that is metabolized to bile acids in the liver. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR.NADPH-ferrihemoprotein reductase).
Protein Name 24-Hydroxycholesterol 7-Alpha-Hydroxylase
Cytochrome P450 39a1
Hcyp39a1
Oxysterol 7-Alpha-Hydroxylase
Database Links Reactome: R-HSA-193775
Reactome: R-HSA-211976
Cellular Localisation Endoplasmic Reticulum Membrane
Multi-Pass Membrane Protein
Microsome Membrane
Alternative Antibody Names Anti-24-Hydroxycholesterol 7-Alpha-Hydroxylase antibody
Anti-Cytochrome P450 39a1 antibody
Anti-Hcyp39a1 antibody
Anti-Oxysterol 7-Alpha-Hydroxylase antibody
Anti-CYP39A1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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