Mouse CYP11A1 (Cytochrome P450 11A1) Sandwich ELISA Kit Ready-To-Use (STJE0014677) STJE0014677|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse CYP11A1 (Cytochrome P450 11A1) Sandwich ELISA Kit Ready-To-Use (STJE0014677)
產品型號：STJE0014677
產品廠商：ST john's laboratory
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簡單介紹：

Mouse CYP11A1 (Cytochrome P450 11A1) Sandwich ELISA Kit Ready-To-Use (STJE0014677)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.133ng/mL
Detection Limit:	0.312-20ng/mL
Short Description:	This CYP11A1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Cyp11a1
Gene ID:	13070
Uniprot ID:	CP11A_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
Protein Name	Cholesterol Side-Chain Cleavage Enzyme - Mitochondrial Cypxia1 Cholesterol Desmolase Cytochrome P450 11a1 Cytochrome P450(Scc
Database Links	Reactome: R-MMU-196108 Reactome: -MMU-211976
Cellular Localisation	Mitochondrion Inner Membrane Peripheral Membrane Protein Localizes To The Matrix Side Of The Mitochondrion Inner Membrane
Alternative ELISA Names	Cholesterol Side-Chain Cleavage Enzyme - Mitochondrial ELISA kit Cypxia1 ELISA kit Cholesterol Desmolase ELISA kit Cytochrome P450 11a1 ELISA kit Cytochrome P450(Scc ELISA kit Cyp11a1 ELISA kit Cyp11a ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse CYP11A1 (Cytochrome P450 11A1) Sandwich ELISA Kit Ready-To-Use (STJE0014677)