產品詳情
簡單介紹:
Anti-DCAF7 antibody (1-342) (STJ28870)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DCAF7 (1-342) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DCAF7 |
Gene ID: | 10238 |
Uniprot ID: | DCAF7_HUMAN |
Immunogen Region: | 1-342 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human DCAF7 (NP_005819.3). |
Immunogen Sequence: | MSLHGKRKEIYKYEAPWTVY AMNWSVRPDKRFRLALGSFV EEYNNKVQLVGLDEESSEFI CRNTFDHPYPTTKLMWIPDT KGVYPDLLATSGDYLRVWRV GETETRLECLLNNNKNSDFC APLTSFDWNEVDPYLLGTSS IDTTCTIWGLETGQVLGRVN LVSGHVKTQLIAHDKEVYDI AFSRAGGGRDMFASVGADGS VRMFDLRHLEHSTIIYEDPQ HHPLLRLCWNKQDPNYLAT |
Function | Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches. Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. |
Protein Name | Ddb1- And Cul4-Associated Factor 7 Wd Repeat-Containing Protein 68 Wd Repeat-Containing Protein An11 Homolog |
Database Links | Reactome: R-HSA-390471 Reactome: R-HSA-8951664 |
Cellular Localisation | Cytoplasm Nucleus Overexpression Of Diahp1 Or Active Rhoa Causes Translocations From The Nucleus To Cytoplasm |
Alternative Antibody Names | Anti-Ddb1- And Cul4-Associated Factor 7 antibody Anti-Wd Repeat-Containing Protein 68 antibody Anti-Wd Repeat-Containing Protein An11 Homolog antibody Anti-DCAF7 antibody Anti-HAN11 antibody Anti-WDR68 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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