Anti-DCP1A antibody (483-582) [S7MR] (STJ11102327) STJ11102327|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DCP1A antibody (483-582) [S7MR] (STJ11102327)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit monoclonal antibody anti-DCP1A (483-582) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.

Clonality:	Monoclonal
Clone ID:	S7MR
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DCP1A
Gene ID:	55802
Uniprot ID:	DCP1A_HUMAN
Immunogen Region:	483-582
Immunogen:	A synthetic peptide corresponding to a sequence within amino acids 483-582 of human DCP1A (Q9NPI6).
Immunogen Sequence:	PVAGAPLVTATTTAVSSVLL APSVFQQTVTRSSDLERKAS SPSPLTIGTPESQRKPSIIL SKSQLQDTLIHLIKNDSSFL STLHEVYLQVLTKNKDNHNL

Tissue Specificity	Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas.
Function	Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. Essential for embryonic development.
Protein Name	Mrna-Decapping Enzyme 1a Smad4-Interacting Transcriptional Co-Activator Transcription Factor Smif
Database Links	Reactome: R-HSA-430039 Reactome: R-HSA-450385 Reactome: R-HSA-450513 Reactome: R-HSA-975957
Cellular Localisation	Cytoplasm P-Body Nucleus Co-Localizes With Nanos3 In The Processing Bodies Predominantly Cytoplasmic In Processing Bodies (Pb) Nuclear After Tgfb1 Treatment Translocations To The Nucleus Depends On Interaction With Smad4
Alternative Antibody Names	Anti-Mrna-Decapping Enzyme 1a antibody Anti-Smad4-Interacting Transcriptional Co-Activator antibody Anti-Transcription Factor Smif antibody Anti-DCP1A antibody Anti-SMIF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DCP1A antibody (483-582) [S7MR] (STJ11102327)