產品詳情
簡單介紹:
Mouse EZH1 (Enhancer Of Zeste Homolog 1) Sandwich ELISA Kit (STJE0008723)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.061ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This EZH1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Ezh1 |
Gene ID: | 14055 |
Uniprot ID: | EZH1_MOUSE |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed at high levels in kidney, adrenal gland, testis and brain. |
Post Translational Modifications | |
Function | Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. |
Protein Name | Histone-Lysine N-Methyltransferase Ezh1 Enx-2 Enhancer Of Zeste Homolog 1 |
Database Links | |
Cellular Localisation | Nucleus Colocalizes With Trimethylated 'Lys-27' Of Histone H3 |
Alternative ELISA Names | Histone-Lysine N-Methyltransferase Ezh1 ELISA kit Enx-2 ELISA kit Enhancer Of Zeste Homolog 1 ELISA kit Ezh1 ELISA kit Enx2 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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