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Anti-DDR2 antibody [3B11E4] (STJ97997) STJ97997|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：Anti-DDR2 antibody [3B11E4] (STJ97997)

  • 產品型號：STJ97997
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
Anti-DDR2 antibody [3B11E4] (STJ97997)
詳情介紹：
Host: Mouse
Applications: WB/IHC/IF/ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Discoidin domain-containing receptor 2 is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Monoclonal
Clone ID: 3B11E4
Conjugation: Unconjugated
Isotype: IgG2a
Formulation: Liquid in PBS containing 0.03% Sodium Azide, 0.5% BSA, 50% Glycerol.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IHC 1:200-1:1000
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: DDR2
Gene ID: 4921
Uniprot ID: DDR2_HUMAN
Specificity: DDR2 Monoclonal Antibody detects endogenous levels of DDR2 protein.
Immunogen: Purified recombinant fragment of human DDR2 expressed in E. Coli.
Post Translational Modifications N-glycosylated. Tyrosine phosphorylated in response to collagen binding. Phosphorylated by SRC.this is required for activation and subsequent autophosphorylation on additional tyrosine residues.
Function Tyrosine kinase involved in the regulation of tissues remodeling. It functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.
Protein Name Discoidin Domain-Containing Receptor 2
Discoidin Domain Receptor 2
Cd167 Antigen-Like Family Member B
Discoidin Domain-Containing Receptor Tyrosine Kinase 2
Neurotrophic Tyrosine Kinase - Receptor-Related 3
Receptor Protein-Tyrosine Kinase Tkt
Tyrosine-Protein Kinase Tyro10
Cd Antigen Cd167b
Database Links Reactome: R-HSA-3000171
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Discoidin Domain-Containing Receptor 2 antibody
Anti-Discoidin Domain Receptor 2 antibody
Anti-Cd167 Antigen-Like Family Member B antibody
Anti-Discoidin Domain-Containing Receptor Tyrosine Kinase 2 antibody
Anti-Neurotrophic Tyrosine Kinase - Receptor-Related 3 antibody
Anti-Receptor Protein-Tyrosine Kinase Tkt antibody
Anti-Tyrosine-Protein Kinase Tyro10 antibody
Anti-Cd Antigen Cd167b antibody
Anti-DDR2 antibody
Anti-NTRKR3 antibody
Anti-TKT antibody
Anti-TYRO10 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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