產品詳情
簡單介紹：
Anti-DEFA3 antibody (20-94) (STJ27293)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DEFA3 (20-94) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DEFA3 |
| Gene ID: | 1668 |
| Uniprot ID: | DEF3_HUMAN |
| Immunogen Region: | 20-94 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-94 of human DEFA3 (NP_005208.1). |
| Immunogen Sequence: | EPLQARADEVAAAPEQIAAD IPEVVVSLAWDESLAPKHPG SRKNMDCYCRIPACIAGERR YGTCIYQGRLWAFCC |
| Function | Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B. anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Blocks also herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment. |
| Protein Name | Neutrophil Defensin 3 Defensin - Alpha 3 Hnp-3 Hp-3 Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2 Hnp-2 Hp-2 Hp2 |
| Database Links | Reactome: R-HSA-1461973 Reactome: R-HSA-1462054 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neutrophil Defensin 3 antibody Anti-Defensin - Alpha 3 antibody Anti-Hnp-3 antibody Anti-Hp-3 antibody Anti-Hp3 Cleaved Into - Hp 3-56 - Neutrophil Defensin 2 antibody Anti-Hnp-2 antibody Anti-Hp-2 antibody Anti-Hp2 antibody Anti-DEFA3 antibody Anti-DEF3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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