Anti-CD317 antibody (55-152) (STJ11105374) STJ11105374|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-CD317 antibody (55-152) (STJ11105374)
產品型號：STJ11105374
產品廠商：ST john's laboratory
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Anti-CD317 antibody (55-152) (STJ11105374)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CD317 (55-152) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:5000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	Bst2
Gene ID:	69550
Uniprot ID:	BST2_MOUSE
Immunogen Region:	55-152
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 55-152 of mouse CD317 (NP_932763.1).
Immunogen Sequence:	SVACRDGLRAQAECRNTTHL LQRQLTRTQDSLLQAETQAN SCNLTVVTLQESLEKKVSQA LEQQARIKELENEVTKLNQE LENLRIQKETSSTVQVNS

Tissue Specificity	In naive mice, specifically expressed on type I interferon-producing cells (at protein level).
Function	IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted. Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), mouse mammary tumor virus (MMTV) and murine leukemia virus (MLV), filoviridae: ebola virus (EBOV), arenaviridae: lassa virus (LASV), and rhabdoviridae: vesicular stomatitis virus (VSV). Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.
Protein Name	Bone Marrow Stromal Antigen 2 Bst-2 Hm1.24 Antigen Cd Antigen Cd317
Database Links	Reactome: R-MMU-6798695
Cellular Localisation	Golgi Apparatus Trans-Golgi Network Cell Membrane Single-Pass Type Ii Membrane Protein Lipid-Anchor Gpi-Anchor Late Endosome Membrane Raft Cytoplasm Apical Cell Membrane Shuttles Between The Cell Membrane Where It Is Present Predominantly In Membrane/Lipid Rafts And The Trans-Golgi Network Forms A Complex With Mmp14 And Localizes To The Cytoplasm
Alternative Antibody Names	Anti-Bone Marrow Stromal Antigen 2 antibody Anti-Bst-2 antibody Anti-Hm1.24 Antigen antibody Anti-Cd Antigen Cd317 antibody Anti-Bst2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CD317 antibody (55-152) (STJ11105374)