產品詳情
簡單介紹：
Anti-DLST antibody (1-290) (STJ115261)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DLST (1-290) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 IHC-P 1:50-1:100 IF/ICC 1:50-1:100 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DLST |
| Gene ID: | 1743 |
| Uniprot ID: | ODO2_HUMAN |
| Immunogen Region: | 1-290 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DLST (NP_001924.2). |
| Immunogen Sequence: | MLSRSRCVSRAFSRSLSAFQ KGNCPLGRRSLPGVSLCQGP GYPNSRKVVINNSVFSVRFF RTTAVCKDDLVTVKTPAFAE SVTEGDVRWEKAVGDTVAED EVVCEIETDKTSVQVPSPAN GVIEALLVPDGGKVEGGTPL FTLRKTGAAPAKAKPAEAPA AAAPKAEPTAAAVPPPAAPI PTQMPPVPSPSQPPSGKPVS AVKPTVAPPLAEPGAGKGLR SEHREKMNRMRQRIAQRLK |
| Function | Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. |
| Protein Name | Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex - Mitochondrial 2-Oxoglutarate Dehydrogenase Complex Component E2 Ogdc-E2 Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex E2k |
| Database Links | Reactome: R-HSA-389661 Reactome: R-HSA-71064 Reactome: R-HSA-71403 |
| Cellular Localisation | Mitochondrion Matrix Nucleus Mainly Localizes In The Mitochondrion A Small Fraction Localizes To The Nucleus Where The 2-Oxoglutarate Dehydrogenase Complex Is Required For Histone Succinylation |
| Alternative Antibody Names | Anti-Dihydrolipoyllysine-Residue Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex - Mitochondrial antibody Anti-2-Oxoglutarate Dehydrogenase Complex Component E2 antibody Anti-Ogdc-E2 antibody Anti-Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex antibody Anti-E2k antibody Anti-DLST antibody Anti-DLTS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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