產品詳情
簡單介紹：
Anti-DOT1L antibody (1-100) [S7MR] (STJ11101407)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IP |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-Dot1L/KMT4 (1-100) is suitable for use in Western Blot and Immunoprecipitation research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S7MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IP 1:500-1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DOT1L |
| Gene ID: | 84444 |
| Uniprot ID: | DOT1L_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Dot1L/KMT4 (NP_115871.1). |
| Immunogen Sequence: | MGEKLELRLKSPVGAEPAVY PWPLPVYDKHHDAAHEIIET IRWVCEEIPDLKLAMENYVL IDYDTKSFESMQRLCDKYNR AIDSIHQLWKGTTQPMKLNT |
| Function | Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. |
| Protein Name | Histone-Lysine N-Methyltransferase - H3 Lysine-79 Specific Dot1-Like Protein Histone H3-K79 Methyltransferase H3-K79-Hmtase Lysine N-Methyltransferase 4 |
| Database Links | Reactome: R-HSA-3214841 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Histone-Lysine N-Methyltransferase - H3 Lysine-79 Specific antibody Anti-Dot1-Like Protein antibody Anti-Histone H3-K79 Methyltransferase antibody Anti-H3-K79-Hmtase antibody Anti-Lysine N-Methyltransferase 4 antibody Anti-DOT1L antibody Anti-KIAA1814 antibody Anti-KMT4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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