產品詳情
簡單介紹:
Anti-DSC1 antibody (824-894) [S5164RM] (STJ11105164)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-Desmocollin-1 (824-894) is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S5164RM |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DSC1 |
Gene ID: | 1823 |
Uniprot ID: | DSC1_HUMAN |
Immunogen Region: | 824-894 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 824-894 of human Desmocollin 1 (NP_077739.1). |
Immunogen Sequence: | QPRLGEKVYLCGQDEEHKHC EDYVCSYNYEGKGSLAGSVG CCSDRQEEEGLEFLDHLEPK FRTLAKTCIKK |
Tissue Specificity | Strongly expressed in epidermis, less in lymph node and tongue. |
Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues. |
Protein Name | Desmocollin-1 Cadherin Family Member 1 Desmosomal Glycoprotein 2/3 Dg2/Dg3 |
Database Links | Reactome: R-HSA-6798695 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Desmosome |
Alternative Antibody Names | Anti-Desmocollin-1 antibody Anti-Cadherin Family Member 1 antibody Anti-Desmosomal Glycoprotein 2/3 antibody Anti-Dg2/Dg3 antibody Anti-DSC1 antibody Anti-CDHF1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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