產品詳情
簡單介紹：
Anti-DSC2 antibody (520-690) (STJ112249)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DSC2 (520-690) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSC2 |
| Gene ID: | 1824 |
| Uniprot ID: | DSC2_HUMAN |
| Immunogen Region: | 520-690 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-690 of human DSC2 (NP_077740.1). |
| Immunogen Sequence: | IDENTGSIKVFRSLDREAET IKNGIYNITVLASDQGGRTC TGTLGIILQDVNDNSPFIPK KTVIICKPTMSSAEIVAVDP DEPIHGPPFDFSLESSTSEV QRMWRLKAINDTAARLSYQN DPPFGSYVVPITVRDRLGMS SVTSLDVTLCDCITENDCTH RVDPRIGGGGV |
| Tissue Specificity | Expressed in the heart (at protein level). |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
| Protein Name | Desmocollin-2 Cadherin Family Member 2 Desmocollin-3 Desmosomal Glycoprotein Ii Desmosomal Glycoprotein Iii |
| Database Links | Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Desmosome |
| Alternative Antibody Names | Anti-Desmocollin-2 antibody Anti-Cadherin Family Member 2 antibody Anti-Desmocollin-3 antibody Anti-Desmosomal Glycoprotein Ii antibody Anti-Desmosomal Glycoprotein Iii antibody Anti-DSC2 antibody Anti-CDHF2 antibody Anti-DSC3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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