產品詳情
簡單介紹：
Anti-DSC3 antibody (576-690) (STJ11104759)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Desmocollin-3 (576-690) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:100-1:500 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSC3 |
| Gene ID: | 1825 |
| Uniprot ID: | DSC3_HUMAN |
| Immunogen Region: | 576-690 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 576-690 of human Desmocollin 3 (NP_001932.2). |
| Immunogen Sequence: | EILQEYVVICKPKMGYTDIL AVDPDEPVHGAPFYFSLPNT SPEISRLWSLTKVNDTAARL SYQKNAGFQEYTIPITVKDR AGQAATKLLRVNLCECTHPT QCRATSRSTGVILGK |
| Tissue Specificity | Epidermis, buccal mucosa, esophagus and cervix. |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. |
| Protein Name | Desmocollin-3 Cadherin Family Member 3 Desmocollin-4 Ht-Cp |
| Database Links | Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Desmosome |
| Alternative Antibody Names | Anti-Desmocollin-3 antibody Anti-Cadherin Family Member 3 antibody Anti-Desmocollin-4 antibody Anti-Ht-Cp antibody Anti-DSC3 antibody Anti-CDHF3 antibody Anti-DSC4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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