產品詳情
簡單介紹：
Anti-DSG2 antibody (635-935) (STJ11100872)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DSG2 (635-935) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSG2 |
| Gene ID: | 1829 |
| Uniprot ID: | DSG2_HUMAN |
| Immunogen Region: | 635-935 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2). |
| Immunogen Sequence: | CHCGKGAKGFTPIPGTIEML HPWNNEGAPPEDKVVPSFLP VDQGGSLVGRNGVGGMAKEA TMKGSSSASIVKGQHEMSEM DGRWEEHRSLLSGRATQFTG ATGAIMTTETTKTARATGAS RDMAGAQAAAVALNEEFLRN YFTDKAASYTEEDENHTAKD CLLVYSQEETESLNASIGCC SFIEGELDDRFLDDLGLKFK TLAEVCLGQKIDINKEIEQR QKPATETSMNTASHSLCEQ |
| Tissue Specificity | All of the tissues tested and carcinomas. |
| Post Translational Modifications | Palmitoylated by ZDHHC5 at the plasma membrane. |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-2 Cadherin Family Member 5 Hdgc |
| Database Links | Reactome: R-HSA-351906 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 Reactome: R-HSA-9013404 Reactome: R-HSA-9013408 Reactome: R-HSA-9013423 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Desmosome |
| Alternative Antibody Names | Anti-Desmoglein-2 antibody Anti-Cadherin Family Member 5 antibody Anti-Hdgc antibody Anti-DSG2 antibody Anti-CDHF5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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