產品詳情
簡單介紹：
Anti-DSG3 antibody (50-615) (STJ11105563)
詳情介紹：
| Host: | Rabbit |
| Applications: | IHC |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Desmoglein-3 (50-615) is suitable for use in Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | IHC-P 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | DSG3 |
| Gene ID: | 1830 |
| Uniprot ID: | DSG3_HUMAN |
| Immunogen Region: | 50-615 |
| Immunogen: | Recombinant Protein corresponding to a sequence within amino acids 50-615 of human DSG3/Desmoglein-3 (NP_001935.2). |
| Immunogen Sequence: | EWVKFAKPCREGEDNSKRNP IAKITSDYQATQKITYRISG VGIDQPPFGIFVVDKNTGDI NITAIVDREETPSFLITCRA LNAQGLDVEKPLILTVKILD INDNPPVFSQQIFMGEIEEN SASNSLVMILNATDADEPNH LNSKIAFKIVSQEPAGTPMF LLSRNTGEVRTLTNSLDREQ ASSYRLVVSGADKDGEGLST QCECNIKVKDVNDNFPMFRD SQYSARIEENILSSELLRF |
| Tissue Specificity | Epidermis, tongue, tonsil, esophagus and carcinomas. Expressed in skin and mucosa (at protein level). |
| Function | Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
| Protein Name | Desmoglein-3 130 Kda Pemphigus Vulgaris Antigen Pva Cadherin Family Member 6 |
| Database Links | Reactome: R-HSA-351906 Reactome: R-HSA-6805567 Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Cell Junction Desmosome |
| Alternative Antibody Names | Anti-Desmoglein-3 antibody Anti-130 Kda Pemphigus Vulgaris Antigen antibody Anti-Pva antibody Anti-Cadherin Family Member 6 antibody Anti-DSG3 antibody Anti-CDHF6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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