Mouse IP10 (Interferon Gamma Induced Protein 10kDa) Sandwich ELISA Kit Ready-To-Use (STJE0016422) STJE0016422|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse IP10 (Interferon Gamma Induced Protein 10kDa) Sandwich ELISA Kit Ready-To-Use (STJE0016422)
產品型號：STJE0016422
產品廠商：ST john's laboratory
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Mouse IP10 (Interferon Gamma Induced Protein 10kDa) Sandwich ELISA Kit Ready-To-Use (STJE0016422)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	5.7pg/mL
Detection Limit:	15.6-1000pg/mL
Short Description:	This IP10 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	Cxcl10
Gene ID:	15945
Uniprot ID:	CXL10_MOUSE
Immunogen Region:	Ready-To-Use
Sample Type:	serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Tissue Specificity	Expressed in the spleen, thymus, lymph nodes and liver. Expressed in astrocytes, microglia, and neurons.
Post Translational Modifications
Function	Pro-inflammatory cytokine that is involved in a wide variety of processes such as chemotaxis, differentiation, and activation of peripheral immune cells, regulation of cell growth, apoptosis and modulation of angiosestatic effects. Plays thereby an important role during viral infections by stimulating the activation and migration of immune cells to the infected sites. Mechanistically, binding of CXCL10 to the CXCR3 receptor activates G protein-mediated signaling and results in downstream activation of phospholipase C-dependent pathway, an increase in intracellular calcium production and actin reorganization. In turn, recruitment of activated Th1 lymphocytes occurs at sites of inflammation. Activation of the CXCL10/CXCR3 axis also plays an important role in neurons in response to brain injury for activating microglia, the resident macrophage population of the central nervous system, and directing them to the lesion site. This recruitment is an essential element for neuronal reorganization.
Protein Name	C-X-C Motif Chemokine 10 10 Kda Interferon Gamma-Induced Protein Gamma-Ip10 Ip-10 C7 Interferon-Gamma Induced Protein Crg-2 Small-Inducible Cytokine B10
Database Links	Reactome: R-MMU-380108 Reactome: -MMU-418594
Cellular Localisation	Secreted
Alternative ELISA Names	C-X-C Motif Chemokine 10 ELISA kit 10 Kda Interferon Gamma-Induced Protein ELISA kit Gamma-Ip10 ELISA kit Ip-10 ELISA kit C7 ELISA kit Interferon-Gamma Induced Protein Crg-2 ELISA kit Small-Inducible Cytokine B10 ELISA kit Cxcl10 ELISA kit Crg2 ELISA kit Ifi10 ELISA kit Inp10 ELISA kit Scyb10 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse IP10 (Interferon Gamma Induced Protein 10kDa) Sandwich ELISA Kit Ready-To-Use (STJE0016422)