產品詳情
簡單介紹:
Mouse KARS (Lysyl tRNA Synthetase) Sandwich ELISA Kit (STJE0010133)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.086ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This KARS Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Kars1 |
Gene ID: | 85305 |
Uniprot ID: | SYK_MOUSE |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Phosphorylated on a serine residue after mast cell stimulation with immunoglobulin E (IgE). |
Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of the signaling molecule diadenosine tetraphosphate (Ap4A), and thereby mediates disruption of the complex between HINT1 and MITF and the concomitant activation of MITF transcriptional activity. |
Protein Name | Lysine--Trna Ligase Lysyl-Trna Synthetase Lysrs |
Database Links | |
Cellular Localisation | Cytoplasm Cytosol Nucleus Cell Membrane Peripheral Membrane Protein Secreted Secretion Is Induced By Tnf-Alpha Cytosolic In Quiescent Mast Cells Translocates Into The Nucleus In Response To Mast Cell Activation By Immunoglobulin E |
Alternative ELISA Names | Lysine--Trna Ligase ELISA kit Lysyl-Trna Synthetase ELISA kit Lysrs ELISA kit Kars1 ELISA kit Kars ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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