產品詳情
簡單介紹:
Anti-CD41/Itga2b antibody [MWReg30] {PE} (STJA0002016)
詳情介紹:
Host: | Rat |
Applications: | FC |
Reactivity: | Mouse |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Short Description: | Rat monoclonal antibody anti-Integrin alpha-IIb is suitable for use in Flow Cytometry research applications. |
Clonality: | Monoclonal |
Clone ID: | MWReg30 |
Conjugation: | PE |
Isotype: | IgG1k |
Formulation: | PBS with 0.05% Proclin300, 1% BSA |
Concentration: | 0.2 mg/mL |
Storage Instruction: | Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product. |
Gene Symbol: | Itga2b |
Gene ID: | 16399 |
Uniprot ID: | ITA2B_MOUSE |
Function | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. |
Protein Name | Integrin Alpha-Iib Gpalpha Iib Gpiib Platelet Membrane Glycoprotein Iib Cd Antigen Cd41 Cleaved Into - Integrin Alpha-Iib Heavy Chain - Integrin Alpha-Iib Light Chain |
Database Links | Reactome: R-MMU-114608 Reactome: -MMU-216083 Reactome: -MMU-3000178 Reactome: -MMU-354192 Reactome: -MMU-354194 Reactome: -MMU-372708 Reactome: -MMU-445144 Reactome: -MMU-5674135 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Integrin Alpha-Iib antibody Anti-Gpalpha Iib antibody Anti-Gpiib antibody Anti-Platelet Membrane Glycoprotein Iib antibody Anti-Cd Antigen Cd41 Cleaved Into - Integrin Alpha-Iib Heavy Chain - Integrin Alpha-Iib Light Chain antibody Anti-Itga2b antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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