產品詳情
簡單介紹:
Anti-DYNLRB1 antibody (1-63) (STJ117391)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-DYNLRB1 (1-63) is suitable for use in Western Blot and Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 IHC-P 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DYNLRB1 |
Gene ID: | 83658 |
Uniprot ID: | DLRB1_HUMAN |
Immunogen Region: | 1-63 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-63 of human DYNLRB1 (NP_001268656.1). |
Immunogen Sequence: | MDNPTTTQYASLMHSFILKA RSTVRDIDPQNDLTFLRIRS KKNEIMVAPDKDYFLIVIQN PTE |
Tissue Specificity | High expression in heart, liver, brain and pancreas.moderate in placenta, skeletal muscle and kidney.low in lung, prostate, testis, small intestine and colon. Isoform 1 expression is up-regulated in 64% hepatocellular carcinoma (HCC) patients. |
Function | Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. |
Protein Name | Dynein Light Chain Roadblock-Type 1 Bithoraxoid-Like Protein Blp Dynein Light Chain 2a - Cytoplasmic Dynein-Associated Protein Km23 Roadblock Domain-Containing Protein 1 |
Database Links | Reactome: R-HSA-5620924 |
Cellular Localisation | Cytoplasm Cytoskeleton |
Alternative Antibody Names | Anti-Dynein Light Chain Roadblock-Type 1 antibody Anti-Bithoraxoid-Like Protein antibody Anti-Blp antibody Anti-Dynein Light Chain 2a - Cytoplasmic antibody Anti-Dynein-Associated Protein Km23 antibody Anti-Roadblock Domain-Containing Protein 1 antibody Anti-DYNLRB1 antibody Anti-BITH antibody Anti-DNCL2A antibody Anti-DNLC2A antibody Anti-ROBLD1 antibody Anti-HSPC162 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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