Anti-DYSF antibody (1981-2030 aa) (STJ92803) STJ92803|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-DYSF antibody (1981-2030 aa) (STJ92803)

詳情介紹：

Host:	Rabbit
Applications:	WB/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Dysferlin (1981-2030 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:10000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	DYSF
Gene ID:	8291
Uniprot ID:	DYSF_HUMAN
Immunogen Region:	1981-2030 aa
Specificity:	Dysferlin Polyclonal Antibody detects endogenous levels of Dysferlin protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human Dysferlin at the amino acid range 1981-2030

Function	Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.
Protein Name	Dysferlin Dystrophy-Associated Fer-1-Like Protein Fer-1-Like Protein 1
Database Links	Reactome: R-HSA-445355
Cellular Localisation	Cell Membrane Sarcolemma Single-Pass Type Ii Membrane Protein Cytoplasmic Vesicle Membrane Colocalizes During Muscle Differentiation With Bin1 In The T-Tubule System Of Myotubules And At The Site Of Contact Between Two Myotubes Or A Myoblast And A Myotube Wounding Of Myotubes Led To Its Focal Enrichment To The Site Of Injury And To Its Relocalization In A Ca(2+)-Dependent Manner Toward The Plasma Membrane Colocalizes With Ahnak Ahnak2 And Parvb At The Sarcolemma Of Skeletal Muscle Detected On The Apical Plasma Membrane Of The Syncytiotrophoblast Reaches The Plasmma Membrane Through A Caveolin-Independent Mechanism Retained By Caveolin At The Plasmma Membrane With Cacna1s In The T-Tubule System Of Myotubules Accumulates And Colocalizes With Fusion Vesicles At The Sarcolemma Disruption Sites
Alternative Antibody Names	Anti-Dysferlin antibody Anti-Dystrophy-Associated Fer-1-Like Protein antibody Anti-Fer-1-Like Protein 1 antibody Anti-DYSF antibody Anti-FER1L1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-DYSF antibody (1981-2030 aa) (STJ92803)