Mouse LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010298) STJE0010298|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010298)
產品型號：STJE0010298
產品廠商：ST john's laboratory
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Mouse LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010298)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.067ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This LDLRAP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Ldlrap1
Gene ID:	100017
Uniprot ID:	ARH_MOUSE
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications
Function	Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR) in polarized cells such as hepatocytes and lymphocytes, but not in non-polarized cells (fibroblasts). May be required for LDL binding and internalization but not for receptor clustering in coated pits. May facilitate the endocytosis of LDLR and LDLR-LDL complexes from coated pits by stabilizing the interaction between the receptor and the structural components of the pits. May also be involved in the internalization of other LDLR family members. Binds to phosphoinositides, which regulate clathrin bud assembly at the cell surface. Required for trafficking of LRP2 to the endocytic recycling compartment which is necessary for LRP2 proteolysis, releasing a tail fragment which translocates to the nucleus and mediates transcriptional repression.
Protein Name	Low Density Lipoprotein Receptor Adapter Protein 1 Autosomal Recessive Hypercholesterolemia Protein Homolog
Database Links	Reactome: R-MMU-8856825 Reactome: -MMU-8856828 Reactome: -MMU-8964026 Reactome: -MMU-8964038 Reactome: -MMU-9758890
Cellular Localisation	Cytoplasm
Alternative ELISA Names	Low Density Lipoprotein Receptor Adapter Protein 1 ELISA kit Autosomal Recessive Hypercholesterolemia Protein Homolog ELISA kit Ldlrap1 ELISA kit Arh ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse LDLRAP1 (Low Density Lipoprotein Receptor Adaptor Protein 1) Sandwich ELISA Kit (STJE0010298)