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Anti-EBF1 antibody (C-Term) (STJ115908) STJ115908|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情
  • 產品名稱:Anti-EBF1 antibody (C-Term) (STJ115908)

  • 產品型號:STJ115908
  • 產品廠商:ST john's laboratory
  • 產品文檔:
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簡單介紹:
Anti-EBF1 antibody (C-Term) (STJ115908)
詳情介紹:
Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EBF1 (C-Term) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EBF1
Gene ID: 1879
Uniprot ID: COE1_HUMAN
Immunogen Region: C-Term
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human EBF1 (NP_076870.1).
Immunogen Sequence: GGSPTFLNGSAANSPYAIVP SSPTMASSTSLPSNCSSSSG IFSFSPANMVSAVKQKSAFA PVVRPQTSPPPTCTSTNGNS LQAISGMIVPPM
Function Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold. (Microbial infection) Acts as a chromatin anchor for Epstein-Barr virus EBNA2 to mediate the assembly of EBNA2 chromatin complexes in B-cells. In addition, binds to the viral LMP1 proximal promoter and promotes its expression during latency.
Protein Name Transcription Factor Coe1
O/E-1
Oe-1
Early B-Cell Factor
Database Links Reactome: R-HSA-381340
Reactome: R-HSA-9752946
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Transcription Factor Coe1 antibody
Anti-O/E-1 antibody
Anti-Oe-1 antibody
Anti-Early B-Cell Factor antibody
Anti-EBF1 antibody
Anti-COE1 antibody
Anti-EBF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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