Anti-EHMT1/GLP1 antibody (950-100) {FITC} (STJ506055) STJ506055-100|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-EHMT1/GLP1 antibody (950-100) {FITC} (STJ506055)
產品型號：STJ506055-100
產品廠商：ST john's laboratory
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Anti-EHMT1/GLP1 antibody (950-100) {FITC} (STJ506055)

詳情介紹：

Host:	Rabbit
Applications:	ELISA/IP/WB
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-EHMT1/GLP1 (950-100) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	FITC
Isotype:	IgG
Purification:	Affinity Purified
Concentration:	0.5-1.5 µg/µl
Dilution Range:	WB: 1:500 ELISA: 1:50, 000 IP: 1:200
Storage Instruction:	Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Gene Symbol:	EHMT1
Gene ID:	79813
Uniprot ID:	EHMT1_HUMAN
Immunogen Region:	950-100
Immunogen:	Synthetic peptide taken within amino acid region 950-100 on human Histone-lysine N-methyltransferase EHMT1/GLP1.

Tissue Specificity	Widely expressed.
Function	Histone methyltransferase that specifically mono- and dimethylates 'Lys-9' of histone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Also weakly methylates 'Lys-27' of histone H3 (H3K27me). Also required for DNA methylation, the histone methyltransferase activity is not required for DNA methylation, suggesting that these 2 activities function independently. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. In addition to the histone methyltransferase activity, also methylates non-histone proteins: mediates dimethylation of 'Lys-373' of p53/TP53. Represses the expression of mitochondrial function-related genes, perhaps by occupying their promoter regions, working in concert with probable chromatin reader BAZ2B.
Protein Name	Histone-Lysine N-Methyltransferase Ehmt1 Euchromatic Histone-Lysine N-Methyltransferase 1 Eu-Hmtase1 G9a-Like Protein 1 Glp Glp1 Histone H3-K9 Methyltransferase 5 H3-K9-Hmtase 5 Lysine N-Methyltransferase 1d
Database Links	Reactome: R-HSA-2559582 Reactome: R-HSA-3214841 Reactome: R-HSA-6804760 Reactome: R-HSA-8853884 Reactome: R-HSA-8953750
Cellular Localisation	Nucleus Chromosome Associates With Euchromatic Regions
Alternative Antibody Names	Anti-Histone-Lysine N-Methyltransferase Ehmt1 antibody Anti-Euchromatic Histone-Lysine N-Methyltransferase 1 antibody Anti-Eu-Hmtase1 antibody Anti-G9a-Like Protein 1 antibody Anti-Glp antibody Anti-Glp1 antibody Anti-Histone H3-K9 Methyltransferase 5 antibody Anti-H3-K9-Hmtase 5 antibody Anti-Lysine N-Methyltransferase 1d antibody Anti-EHMT1 antibody Anti-EUHMTASE1 antibody Anti-GLP antibody Anti-KIAA1876 antibody Anti-KMT1D antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-EHMT1/GLP1 antibody (950-100) {FITC} (STJ506055)