產品詳情
簡單介紹:
Mouse NRP1 (Neuropilin 1) Sandwich ELISA Kit (STJE0011091)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.065ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This NRP1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | Nrp1 |
Gene ID: | 18186 |
Uniprot ID: | NRP1_MOUSE |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Nervous system. |
Post Translational Modifications | |
Function | Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. Regulates VEGF-induced angiogenesis. Binding to VEGFA initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Regulates mitochondrial iron transport via interaction with ABCB8/MITOSUR. |
Protein Name | Neuropilin-1 A5 Protein Cd Antigen Cd304 |
Database Links | Reactome: R-MMU-194306 Reactome: -MMU-399954 Reactome: -MMU-399955 Reactome: -MMU-399956 Reactome: -MMU-445144 |
Cellular Localisation | Mitochondrion Membrane Single-Pass Type I Membrane Protein Cell Membrane Cytoplasm |
Alternative ELISA Names | Neuropilin-1 ELISA kit A5 Protein ELISA kit Cd Antigen Cd304 ELISA kit Nrp1 ELISA kit Nrp ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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