產品詳情
簡單介紹:
Mouse Pgp (Permeability Glycoprotein) Sandwich ELISA Kit Ready-To-Use (STJE0017825)
詳情介紹:
Applications: | ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.051ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This Pgp Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | Abcb1b |
Gene ID: | 18669 |
Uniprot ID: | MDR1B_MOUSE |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Several phosphorylated serine residues are present in the linker domain. |
Function | Translocates drugs and phospholipids across the membrane. Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins. Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. |
Protein Name | Atp-Dependent Translocase Abcb1 Atp-Binding Cassette Sub-Family B Member 1b Multidrug Resistance Protein 1b P-Glycoprotein 1 Phospholipid Transporter Abcb1 Cd Antigen Cd243 |
Database Links | |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Apical Cell Membrane Cytoplasm Abcb1 Localization Is Influenced By C1orf115 Expression Levels (Plasma Membrane Versus Cytoplasm) |
Alternative ELISA Names | Atp-Dependent Translocase Abcb1 ELISA kit Atp-Binding Cassette Sub-Family B Member 1b ELISA kit Multidrug Resistance Protein 1b ELISA kit P-Glycoprotein 1 ELISA kit Phospholipid Transporter Abcb1 ELISA kit Cd Antigen Cd243 ELISA kit Abcb1b ELISA kit Abcb1 ELISA kit Mdr1 ELISA kit Mdr1b ELISA kit Pgy1 ELISA kit Pgy1-1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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