Mouse PICK1 (Protein Interacting With Protein Kinase C Alpha 1) Sandwich ELISA Kit (STJE0011453) STJE0011453|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Mouse PICK1 (Protein Interacting With Protein Kinase C Alpha 1) Sandwich ELISA Kit (STJE0011453)
產品型號：STJE0011453
產品廠商：ST john's laboratory
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Mouse PICK1 (Protein Interacting With Protein Kinase C Alpha 1) Sandwich ELISA Kit (STJE0011453)

詳情介紹：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.053ng/mL
Detection Limit:	0.156-10ng/mL
Short Description:	This PICK1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Pick1Uniprot ID=PICK1_MOUSE"
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Expressed in all tissues examined, with highest levels in brain and testes and lowest levels in lung.
Post Translational Modifications	Phosphorylation at Thr-82 appears to inhibit the interaction with AMPA receptors. Phosphorylated on tyrosine residues by EPHB2 and on serine or threonine residues by PKC. Palmitoylation on Cys-414 is essential for long-term synaptic depression (LTD).
Function	Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex.the function is competitive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.
Protein Name	Prkca-Binding Protein Protein Interacting With C Kinase 1 Protein Kinase C-Alpha-Binding Protein
Database Links
Cellular Localisation	Cytoplasm Perinuclear Region Membrane Peripheral Membrane Protein Lipid-Anchor Postsynaptic Density Synapse Synaptosome Cytoskeleton Also Membrane-Associated Present At Excitatory Synapses
Alternative ELISA Names	Prkca-Binding Protein ELISA kit Protein Interacting With C Kinase 1 ELISA kit Protein Kinase C-Alpha-Binding Protein ELISA kit Pick1 ELISA kit Prkcabp ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Mouse PICK1 (Protein Interacting With Protein Kinase C Alpha 1) Sandwich ELISA Kit (STJE0011453)