Anti-EPHB4 antibody (571-620 aa) (STJ92952) STJ92952|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-EPHB4 antibody (571-620 aa) (STJ92952)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Ephrin type-B receptor 4 (571-620 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 IF 1:200-1:1000 ELISA 1:20000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	EPHB4
Gene ID:	2050
Uniprot ID:	EPHB4_HUMAN
Immunogen Region:	571-620 aa
Specificity:	EphB4 Polyclonal Antibody detects endogenous levels of EphB4 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human EPHB4 at the amino acid range 571-620

Post Translational Modifications	Phosphorylated.autophosphorylation is stimulated by EFNB2.
Function	Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 it is involved in the regulation of cell adhesion and migration, and plays a central role in heart morphogenesis, angiogenesis and blood vessel remodeling and permeability. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells.
Protein Name	Ephrin Type-B Receptor 4 Hepatoma Transmembrane Kinase Tyrosine-Protein Kinase Tyro11
Database Links	Reactome: R-HSA-2682334 Reactome: R-HSA-3928662 Reactome: R-HSA-3928664 Reactome: R-HSA-3928665
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Ephrin Type-B Receptor 4 antibody Anti-Hepatoma Transmembrane Kinase antibody Anti-Tyrosine-Protein Kinase Tyro11 antibody Anti-EPHB4 antibody Anti-HTK antibody Anti-MYK1 antibody Anti-TYRO11 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-EPHB4 antibody (571-620 aa) (STJ92952)