Anti-EPN1 antibody (130-180) (STJ119738) STJ119738|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-EPN1 antibody (130-180) (STJ119738)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-EPN1 (130-180) is suitable for use in Western Blot and Immunohistochemistry research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000 IHC-P 1:50-1:200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	EPN1
Gene ID:	29924
Uniprot ID:	EPN1_HUMAN
Immunogen Region:	130-180
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 130-180 of human EPN1 (NP_037465.2).
Immunogen Sequence:	LVALLRDEDRLREERAHALK TKEKLAQTATASSAAVGSGP PPEAEQAWPQS

Post Translational Modifications	Phosphorylated on serine and/or threonine residues in mitotic cells. Phosphorylation reduces interaction with REPS2, AP-2 and the membrane fraction. Depolarization of synaptosomes results in dephosphorylation. Ubiquitinated.
Function	Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis.
Protein Name	Epsin-1 Eh Domain-Binding Mitotic Phosphoprotein Eps-15-Interacting Protein 1
Database Links	Reactome: R-HSA-182971 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828
Cellular Localisation	Cytoplasm Cell Membrane Peripheral Membrane Protein Nucleus Membrane Clathrin-Coated Pit Associated With The Cytoplasmic Membrane At Sites Where Clathrin-Coated Pits Are Forming Colocalizes With Clathrin And Ap-2 In A Punctate Pattern On The Plasma Membrane Detected In Presynaptic Nerve Terminals And In Golgi Stacks May Shuttle To The Nucleus When Associated With Zbtb16/Znf145
Alternative Antibody Names	Anti-Epsin-1 antibody Anti-Eh Domain-Binding Mitotic Phosphoprotein antibody Anti-Eps-15-Interacting Protein 1 antibody Anti-EPN1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-EPN1 antibody (130-180) (STJ119738)