Anti-ERCC1 antibody (141-190 aa) (STJ92979) STJ92979|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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Anti-ERCC1 antibody (141-190 aa) (STJ92979)

詳情介紹：

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-DNA excision repair protein ERCC-1 (141-190 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	ERCC1
Gene ID:	2067
Uniprot ID:	ERCC1_HUMAN
Immunogen Region:	141-190 aa
Specificity:	ERCC1 Polyclonal Antibody detects endogenous levels of ERCC1 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human ERCC1 at the amino acid range 141-190

Function	Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. Isoform 2: Not functional in the nucleotide excision repair pathway. Isoform 3: Not functional in the nucleotide excision repair pathway. Isoform 4: Not functional in the nucleotide excision repair pathway.
Protein Name	Dna Excision Repair Protein Ercc-1
Database Links	Reactome: R-HSA-5685938 Reactome: R-HSA-5696395 Reactome: R-HSA-5696400 Reactome: R-HSA-6782135 Reactome: R-HSA-6783310
Cellular Localisation	Isoform 1: Nucleus Isoform 2: Cytoplasm Nucleus Isoform 3: Nucleus Isoform 4: Nucleus
Alternative Antibody Names	Anti-Dna Excision Repair Protein Ercc-1 antibody Anti-ERCC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-ERCC1 antibody (141-190 aa) (STJ92979)