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Anti-ERCC1 antibody [1B10] (STJ96980) STJ96980|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：Anti-ERCC1 antibody [1B10] (STJ96980)

  • 產品型號：STJ96980
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
Anti-ERCC1 antibody [1B10] (STJ96980)
詳情介紹：
Host: Mouse
Applications: WB/IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-DNA excision repair protein ERCC-1 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: 1B10
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range: IHC-P 100-300
WB 1:1000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ERCC1
Gene ID: 2067
Uniprot ID: ERCC1_HUMAN
Specificity: The antibody detects endogenous ERCC1 proteins.
Immunogen: Synthetic Peptide of ERCC1
Function Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. Isoform 2: Not functional in the nucleotide excision repair pathway. Isoform 3: Not functional in the nucleotide excision repair pathway. Isoform 4: Not functional in the nucleotide excision repair pathway.
Protein Name Dna Excision Repair Protein Ercc-1
Database Links Reactome: R-HSA-5685938
Reactome: R-HSA-5696395
Reactome: R-HSA-5696400
Reactome: R-HSA-6782135
Reactome: R-HSA-6783310
Cellular Localisation Isoform 1: Nucleus
Isoform 2: Cytoplasm
Nucleus
Isoform 3: Nucleus
Isoform 4: Nucleus
Alternative Antibody Names Anti-Dna Excision Repair Protein Ercc-1 antibody
Anti-ERCC1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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