產品詳情
簡單介紹:
Anti-ESRP2 antibody (STJ191810)
詳情介紹:
Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Epithelial splicing regulatory protein 2 is suitable for use in Western Blot and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | ESRP2 |
Gene ID: | 80004 |
Uniprot ID: | ESRP2_HUMAN |
Specificity: | ESRP2 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein |
Function | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. |
Protein Name | Epithelial Splicing Regulatory Protein 2 Rna-Binding Motif Protein 35b Rna-Binding Protein 35b |
Database Links | Reactome: R-HSA-6803529 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Epithelial Splicing Regulatory Protein 2 antibody Anti-Rna-Binding Motif Protein 35b antibody Anti-Rna-Binding Protein 35b antibody Anti-ESRP2 antibody Anti-RBM35B antibody Anti-PP7059 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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