產品詳情
簡單介紹：
Anti-F11 antibody (491-540 aa) (STJ193904)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Coagulation factor XI (491-540 aa) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | F11 |
| Gene ID: | 2160 |
| Uniprot ID: | FA11_HUMAN |
| Immunogen Region: | 491-540 aa |
| Specificity: | This antibody detects endogenous levels of FA11 at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human FA11 at the amino acid range 491-540 |
| Post Translational Modifications | N-glycosylated on both chains. N-glycosylated sites mainly consist of nonfucosylated sialylated biantennary (in high abundance) and/or triantennary (in low abundance) complex structures. Glycosylation at Asn-163 uses a rare non-canonical Asn-X-Cys glycosite. Activated by factor XIIa (or XII), which cleaves each polypeptide after Arg-387 into the light chain, which contains the active site, and the heavy chain, which associates with high molecular weight (HMW) kininogen. |
| Function | Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. |
| Protein Name | Coagulation Factor Xi Fxi Plasma Thromboplastin Antecedent Pta Cleaved Into - Coagulation Factor Xia Heavy Chain - Coagulation Factor Xia Light Chain |
| Database Links | Reactome: R-HSA-140837 Reactome: R-HSA-9673221 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Coagulation Factor Xi antibody Anti-Fxi antibody Anti-Plasma Thromboplastin Antecedent antibody Anti-Pta Cleaved Into - Coagulation Factor Xia Heavy Chain - Coagulation Factor Xia Light Chain antibody Anti-F11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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