產品詳情
簡單介紹:
Anti-F13A1 antibody (600-732) (STJ29855)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-F13A1 (600-732) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | F13A1 |
Gene ID: | 2162 |
Uniprot ID: | F13A_HUMAN |
Immunogen Region: | 600-732 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 600-732 of human F13A1 (NP_000120.2). |
Immunogen Sequence: | LEQASLHFFVTARINETRDV LAKQKSTVLTIPEIIIKVRG TQVVGSDMTVTVEFTNPLKE TLRNVWVHLDGPGVTRPMKK MFREIRPNSTVQWEEVCRPW VSGHRKLIASMSSDSLRHVY GELDVQIQRRPSM |
Post Translational Modifications | The activation peptide is released by thrombin. |
Function | Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. |
Protein Name | Coagulation Factor Xiii A Chain Coagulation Factor Xiiia Protein-Glutamine Gamma-Glutamyltransferase A Chain Transglutaminase A Chain |
Database Links | Reactome: R-HSA-114608 Reactome: R-HSA-140875 Reactome: R-HSA-6785807 |
Cellular Localisation | Cytoplasm Secreted Secreted Into The Blood Plasma Cytoplasmic In Most Tissues But Also Secreted In The Blood Plasma |
Alternative Antibody Names | Anti-Coagulation Factor Xiii A Chain antibody Anti-Coagulation Factor Xiiia antibody Anti-Protein-Glutamine Gamma-Glutamyltransferase A Chain antibody Anti-Transglutaminase A Chain antibody Anti-F13A1 antibody Anti-F13A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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