產品詳情
簡單介紹：
Anti-FAAH antibody (480-579) [S6MR] (STJ11101996)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-FAAH1 (480-579) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S6MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:1000 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAAH |
| Gene ID: | 2166 |
| Uniprot ID: | FAAH1_HUMAN |
| Immunogen Region: | 480-579 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 480-579 of human FAAH1 (O00519). |
| Immunogen Sequence: | DLNAPGRATGAVSYTMLYNC LDFPAGVVPVTTVTAEDEAQ MEHYRGYFGDIWDKMLQKGM KKSVGLPVAVQCVALPWQEE LCLRFMREVERLMTPEKQSS |
| Tissue Specificity | Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate. |
| Function | Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates. It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids. |
| Protein Name | Fatty-Acid Amide Hydrolase 1 Anandamide Amidohydrolase 1 Fatty Acid Ester Hydrolase Oleamide Hydrolase 1 |
| Database Links | Reactome: R-HSA-2142753 |
| Cellular Localisation | Endomembrane System Single-Pass Membrane Protein Cytoplasm Cytoskeleton Seems To Be Attached To Intracellular Membranes And A Portion Of The Cytoskeletal Network |
| Alternative Antibody Names | Anti-Fatty-Acid Amide Hydrolase 1 antibody Anti-Anandamide Amidohydrolase 1 antibody Anti-Fatty Acid Ester Hydrolase antibody Anti-Oleamide Hydrolase 1 antibody Anti-FAAH antibody Anti-FAAH1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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