產品詳情
簡單介紹：
Mouse TPM2 (Tropomyosin 2 Beta) Sandwich ELISA Kit (STJE0012761)
詳情介紹：
| Applications: | ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.278ng/mL |
| Detection Limit: | 0.625-40ng/mL |
| Short Description: | This TPM2 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | Tpm2 |
| Gene ID: | 22004 |
| Uniprot ID: | TPM2_MOUSE |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | |
| Post Translational Modifications | Phosphorylated on Ser-61 by PIK3CG. Phosphorylation on Ser-61 is required for ADRB2 internalization. |
| Function | Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. |
| Protein Name | Tropomyosin Beta Chain Beta-Tropomyosin Tropomyosin-2 |
| Database Links | Reactome: R-MMU-390522 Reactome: -MMU-445355 |
| Cellular Localisation | Cytoplasm Cytoskeleton Associates With F-Actin Stress Fibers |
| Alternative ELISA Names | Tropomyosin Beta Chain ELISA kit Beta-Tropomyosin ELISA kit Tropomyosin-2 ELISA kit Tpm2 ELISA kit Tpm-2 ELISA kit |
| output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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