產品詳情
簡單介紹:
Anti-FBP2 antibody (1-339) (STJ111892)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FBP2 (1-339) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FBP2 |
Gene ID: | 8789 |
Uniprot ID: | F16P2_HUMAN |
Immunogen Region: | 1-339 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human FBP2 (NP_003828.2). |
Immunogen Sequence: | MTDRSPFETDMLTLTRYVME KGRQAKGTGELTQLLNSMLT AIKAISSAVRKAGLAHLYGI AGSVNVTGDEVKKLDVLSNS LVINMVQSSYSTCVLVSEEN KDAIITAKEKRGKYVVCFDP LDGSSNIDCLASIGTIFAIY RKTSEDEPSEKDALQCGRNI VAAGYALYGSATLVALSTGQ GVDLFMLDPALGEFVLVEKD VKIKKKGKIYSLNEGYAKYF DAATTEYVQKKKFPEDGSA |
Tissue Specificity | Expressed in skeletal muscle (at protein level). |
Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
Protein Name | Fructose-1 -6-Bisphosphatase Isozyme 2 Fbpase 2 D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 Muscle Fbpase |
Database Links | Reactome: R-HSA-70263 |
Cellular Localisation | Cell Junction Cytoplasm Nucleus Myofibril Sarcomere Z Line In Neonatal Cardiomyocytes Distributed Throughout The Cytosol Accumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent Cells And Also Located In The Nucleus Dissociates From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration In Muscle Precursor Cells Localizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative Phase While Mainly Localizing To The Cytoplasm At The Differentiation Phase Colocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal Muscle Dissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration |
Alternative Antibody Names | Anti-Fructose-1 -6-Bisphosphatase Isozyme 2 antibody Anti-Fbpase 2 antibody Anti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 antibody Anti-Muscle Fbpase antibody Anti-FBP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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