產品詳情
簡單介紹:
Anti-FBXO32 antibody (240-280) {Biotin} (STJ500184)
詳情介紹:
Host: | Rabbit |
Applications: | ELISA/IHC/IP/WB |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FBXO32 (240-280) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Biotin |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.64-0.72 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:50-1:150 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | FBXO32 |
Gene ID: | 114907 |
Uniprot ID: | FBX32_HUMAN |
Immunogen Region: | 240-280 |
Immunogen: | Synthetic peptide taken within amino acid region 240-280 on Atr1 protein. |
Tissue Specificity | Specifically expressed in cardiac and skeletal muscle. |
Function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1. |
Protein Name | F-Box Only Protein 32 Atrogin-1 Muscle Atrophy F-Box Protein Mafbx |
Database Links | Reactome: R-HSA-8951664 Reactome: R-HSA-9615017 Reactome: R-HSA-983168 |
Cellular Localisation | Cytoplasm Nucleus Shuttles Between Cytoplasm And The Nucleus |
Alternative Antibody Names | Anti-F-Box Only Protein 32 antibody Anti-Atrogin-1 antibody Anti-Muscle Atrophy F-Box Protein antibody Anti-Mafbx antibody Anti-FBXO32 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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