Anti-CDCP1 antibody (30-343) (STJ116082) STJ116082|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-CDCP1 antibody (30-343) (STJ116082)
產品型號：STJ116082
產品廠商：ST john's laboratory
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簡單介紹：

Anti-CDCP1 antibody (30-343) (STJ116082)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-CDCP1 (30-343) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:500-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDCP1
Gene ID:	64866
Uniprot ID:	CDCP1_HUMAN
Immunogen Region:	30-343
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 30-343 of human CDCP1 (NP_835488.1).
Immunogen Sequence:	FEIALPRESNITVLIKLGTP TLLAKPCYIVISKRHITMLS IKSGERIVFTFSCQSPENHF VIEIQKNIDCMSGPCPFGEV QLQPSTSLLPTLNRTFIWDV KAHKSIGLELQFSIPRLRQI GPGESCPDGVTHSISGRIDA TVVRIGTFCSNGTVSRIKMQ EGVKMALHLPWFHPRNVSGF SIANRSSIKRLCIIESVFEG EGSATLMSANYPEGFPEDEL MTWQFVVPAHLRASVSFLN

Tissue Specificity	Highly expressed in mitotic cells with low expression during interphase. Detected at highest levels in skeletal muscle and colon with lower levels in kidney, small intestine, placenta and lung. Up-regulated in a number of human tumor cell lines, as well as in colorectal cancer, breast carcinoma and lung cancer. Also expressed in cells with phenotypes reminiscent of mesenchymal stem cells and neural stem cells.
Post Translational Modifications	Phosphorylated on tyrosine by kinases of the SRC family such as SRC and YES as well as by the protein kinase C gamma/PRKCG. Dephosphorylated by phosphotyrosine phosphatases. Also phosphorylated by suramin, a heparin analog. Tyrosine phosphorylated in response to dissociation of integrin alpha-6 beta-4 from laminin-5. N-glycosylated. A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding). Another peptide of 80 kDa (p80) is present in cultured keratinocytes probably due to tryptic cleavage at an unidentified site on its N-terminal side. Converted to p80 by plasmin, a trypsin-like protease.
Function	May be involved in cell adhesion and cell matrix association. May play a role in the regulation of anchorage versus migration or proliferation versus differentiation via its phosphorylation. May be a novel marker for leukemia diagnosis and for immature hematopoietic stem cell subsets. Belongs to the tetraspanin web involved in tumor progression and metastasis.
Protein Name	Cub Domain-Containing Protein 1 Membrane Glycoprotein Gp140 Subtractive Immunization M Plus Hep3-Associated 135 Kda Protein Sima135 Transmembrane And Associated With Src Kinases Cd Antigen Cd318
Cellular Localisation	Isoform 1: Cell Membrane Single-Pass Membrane Protein Shedding May Also Lead To A Soluble Peptide Isoform 3: Secreted
Alternative Antibody Names	Anti-Cub Domain-Containing Protein 1 antibody Anti-Membrane Glycoprotein Gp140 antibody Anti-Subtractive Immunization M Plus Hep3-Associated 135 Kda Protein antibody Anti-Sima135 antibody Anti-Transmembrane And Associated With Src Kinases antibody Anti-Cd Antigen Cd318 antibody Anti-CDCP1 antibody Anti-TRASK antibody Anti-UNQ2486 antibody Anti-PRO5773 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-CDCP1 antibody (30-343) (STJ116082)