產品詳情
簡單介紹:
Anti-FCAR antibody (60-287) (STJ111464)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FCAR (60-287) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:200-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FCAR |
Gene ID: | 2204 |
Uniprot ID: | FCAR_HUMAN |
Immunogen Region: | 60-287 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1). |
Immunogen Sequence: | LMIIKNSTYREIGRRLKFWN ETDPEFVIDHMDANKAGRYQ CQYRIGHYRFRYSDTLELVV TGLYGKPFLSADRGLVLMPG ENISLTCSSAHIPFDRFSLA KEGELSLPQHQSGEHPANFS LGPVDLNVSGIYRCYGWYNR SPYLWSFPSNALELVVTDSI HQDYTTQNLIRMAVAGLVLV ALLAILVENWHSHTALNKEA SADVAEPSWSQQMCQPGLTF ARTPSVCK |
Tissue Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages.however only one isoform is expressed at alveolar macrophages surfaces. |
Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. |
Protein Name | Immunoglobulin Alpha Fc Receptor Iga Fc Receptor Cd Antigen Cd89 |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | Isoform A 1: Cell Membrane Single-Pass Type I Membrane Protein 2: Cell Membrane 3: Cell Membrane Isoform B: Secreted Isoform B-Delta-S2: Secreted |
Alternative Antibody Names | Anti-Immunoglobulin Alpha Fc Receptor antibody Anti-Iga Fc Receptor antibody Anti-Cd Antigen Cd89 antibody Anti-FCAR antibody Anti-CD89 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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