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Anti-FCER1A antibody (STJA0010299) STJA0010299|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司
產品詳情

  • 產品名稱：Anti-FCER1A antibody (STJA0010299)

  • 產品型號：STJA0010299
  • 產品廠商：ST john's laboratory
  • 產品文檔：
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簡單介紹：
Anti-FCER1A antibody (STJA0010299)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-High affinity immunoglobulin epsilon receptor subunit alpha is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FCER1A
Gene ID: 2205
Uniprot ID: FCERA_HUMAN
Specificity: This antibody detects endogenous levels of FCER1A at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human FCER1A
Tissue Specificity Expressed in eosinophils.
Function High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
Protein Name High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha
Fc-Epsilon Ri-Alpha
Fceri
Ige Fc Receptor Subunit Alpha
Database Links Reactome: R-HSA-2454202
Reactome: R-HSA-2730905
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-2871837
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha antibody
Anti-Fc-Epsilon Ri-Alpha antibody
Anti-Fceri antibody
Anti-Ige Fc Receptor Subunit Alpha antibody
Anti-FCER1A antibody
Anti-FCE1A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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