Anti-FCER1G antibody (19-86) (STJ114755) STJ114755|產品目錄|代理商|上海91麻豆福利视频网生物科技有限公司

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產品名稱：Anti-FCER1G antibody (19-86) (STJ114755)
產品型號：STJ114755
產品廠商：ST john's laboratory
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Anti-FCER1G antibody (19-86) (STJ114755)

詳情介紹：

Host:	Rabbit
Applications:	WB
Reactivity:	Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-FCER1G (19-86) is suitable for use in Western Blot research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification:	Affinity purification
Dilution Range:	WB 1:1000-1:2000
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	FCER1G
Gene ID:	2207
Uniprot ID:	FCERG_HUMAN
Immunogen Region:	19-86
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 19-86 of human FCER1G (NP_004097.1).
Immunogen Sequence:	LGEPQLCYILDAILFLYGIV LTLLYCRLKIQVRKAAITSY EKSDGVYTGLSTRNQETYET LKHEKPPQ

Function	Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functional signaling complex in myeloid cells. Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of ITAM, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes. May function cooperatively with other activating receptors. Functionally linked to integrin beta-2/ITGB2-mediated neutrophil activation. Also involved in integrin alpha-2/ITGA2-mediated platelet activation.
Protein Name	High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma Fc Receptor Gamma-Chain Fcrgamma Fc-Epsilon Ri-Gamma Ige Fc Receptor Subunit Gamma Fceri Gamma
Database Links	Reactome: R-HSA-114604 Reactome: R-HSA-202733 Reactome: R-HSA-2454202 Reactome: R-HSA-2730905 Reactome: R-HSA-2871796 Reactome: R-HSA-2871809 Reactome: R-HSA-2871837 Reactome: R-HSA-5621480 Reactome: R-HSA-6798695 Reactome: R-HSA-75892
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-High Affinity Immunoglobulin Epsilon Receptor Subunit Gamma antibody Anti-Fc Receptor Gamma-Chain antibody Anti-Fcrgamma antibody Anti-Fc-Epsilon Ri-Gamma antibody Anti-Ige Fc Receptor Subunit Gamma antibody Anti-Fceri Gamma antibody Anti-FCER1G antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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產品名稱：Anti-FCER1G antibody (19-86) (STJ114755)