產品詳情
簡單介紹：
Anti-FCGR2B antibody (141-190 aa) (STJ96611)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Low affinity immunoglobulin gamma Fc region receptor II-b (141-190 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FCGR2B |
| Gene ID: | 2213 |
| Uniprot ID: | FCG2B_HUMAN |
| Immunogen Region: | 141-190 aa |
| Specificity: | CD32-B/C Polyclonal Antibody detects endogenous levels of CD32-B/C protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human FCGR2B/C at the amino acid range 141-190 |
| Post Translational Modifications | Phosphorylated by the SRC-type Tyr-kinases LYN and BLK. |
| Function | Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. |
| Protein Name | Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B Igg Fc Receptor Ii-B Cdw32 Fc-Gamma Rii-B Fc-Gamma-Riib Fcrii-B Cd Antigen Cd32 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-B antibody Anti-Igg Fc Receptor Ii-B antibody Anti-Cdw32 antibody Anti-Fc-Gamma Rii-B antibody Anti-Fc-Gamma-Riib antibody Anti-Fcrii-B antibody Anti-Cd Antigen Cd32 antibody Anti-FCGR2B antibody Anti-CD32 antibody Anti-FCG2 antibody Anti-IGFR2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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