產品詳情
簡單介紹：
Anti-CDHR1 antibody (20-300) (STJ119835)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-CDHR1 (20-300) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CDHR1 |
| Gene ID: | 92211 |
| Uniprot ID: | CDHR1_HUMAN |
| Immunogen Region: | 20-300 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human CDHR1 (NP_001165442.1). |
| Immunogen Sequence: | QANFAPHFFDNGVGSTNGNM ALFSLPEDTPVGSHVYTLNG TDPEGDPISYHISFDPSTRS VFSVDPTFGNITLVEELDRE REDEIEAIISISDGLNLVAE KVVILVTDANDEAPRFIQEP YVALVPEDIPAGSIIFKVHA VDRDTGSGGSVTYFLQNLHS PFAVDRHSGVLRLQAGATLD YERSRTHYITVVAKDGGGRL HGADVVFSATTTVTVNVEDV QDMAPVFVGTPYYGYVYED |
| Post Translational Modifications | Undergoes proteolytic cleavage.produces a soluble 95 kDa N-terminal fragment and a 25 kDa cell-associated C-terminal fragment. |
| Function | Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells. |
| Protein Name | Cadherin-Related Family Member 1 Photoreceptor Cadherin Prcad Protocadherin-21 |
| Cellular Localisation | Cell Membrane Single-Pass Membrane Protein Localized At The Junction Between The Inner And Outer Segments Of Rod And Cone Photoreceptors Cells Confined To The Base Of The Os Localized On The Edges Of Nascent Evaginating Disks On The Side Of The Os Opposite The Connecting Cilium Expressed At Postnatal Day 2 At The Apical Tip Of The Rod Photoreceptor Cells The Site Of The Developing Os Colocalized With Rhodopsin Between Postnatal Days 2 And 9 At The Base Of The Growing Os Region |
| Alternative Antibody Names | Anti-Cadherin-Related Family Member 1 antibody Anti-Photoreceptor Cadherin antibody Anti-Prcad antibody Anti-Protocadherin-21 antibody Anti-CDHR1 antibody Anti-KIAA1775 antibody Anti-PCDH21 antibody Anti-PRCAD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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