產品詳情
簡單介紹:
Anti-FGD4 antibody (99-198) (STJ111328)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FGD4 (99-198) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FGD4 |
Gene ID: | 121512 |
Uniprot ID: | FGD4_HUMAN |
Immunogen Region: | 99-198 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2). |
Immunogen Sequence: | QMECEEEKAATLSSDTSIQA SEPLLDTHIVNGERDETATA PASPTTDSCDGNASDSSYRT PGIGPVLPLEERGAETETKV QERENGESPLELEQLDQHHE |
Tissue Specificity | Expressed in different tissues, including brain, cerebellum, peripheral nerve, skeletal muscle, heart, uterus, placenta and testis. |
Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. |
Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 4 Actin Filament-Binding Protein Frabin Fgd1-Related F-Actin-Binding Protein Zinc Finger Fyve Domain-Containing Protein 6 |
Database Links | Reactome: R-HSA-193648 Reactome: R-HSA-416482 Reactome: R-HSA-9013148 |
Cellular Localisation | Cytoplasm Cytoskeleton Cell Projection Filopodium Concentrated In Filopodia And Poorly Detected At Lamellipodsia Binds Along The Sides Of Actin Fibers |
Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 4 antibody Anti-Actin Filament-Binding Protein Frabin antibody Anti-Fgd1-Related F-Actin-Binding Protein antibody Anti-Zinc Finger Fyve Domain-Containing Protein 6 antibody Anti-FGD4 antibody Anti-FRABP antibody Anti-ZFYVE6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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