產品詳情
簡單介紹:
Anti-FMNL1 antibody (900-1070) (STJ114977)
詳情介紹:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FMNL1 (900-1070) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FMNL1 |
Gene ID: | 752 |
Uniprot ID: | FMNL1_HUMAN |
Immunogen Region: | 900-1070 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2). |
Immunogen Sequence: | DLHFLDKAGSVSLDSVLADV RSLQRGLELTQREFVRQDDC MVLKEFLRANSPTMDKLLAD SKTAQEAFESVVEYFGENPK TTSPGLFFSLFSRFIKAYKK AEQEVEQWKKEAAAQEAGAD TPGKGEPPAPKSPPKARRPQ MDLISELKRRQQKEPLIYES DRDGAIEDIIT |
Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
Post Translational Modifications | Myristoylation mediates membrane localization and blebbing. |
Function | May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. |
Protein Name | Formin-Like Protein 1 Cll-Associated Antigen Kw-13 Leukocyte Formin |
Database Links | Reactome: R-HSA-5663220 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 |
Cellular Localisation | Cytoplasm Cell Membrane Lipid-Anchor Cytoplasmic Vesicle Phagosome Recruited To Actin-Rich Phagosomes During Phagocytosis Translocates To The Plasma Membrane Upon Activation By Rac1 Isoform 3: Cytoplasm Cell Cortex Cell Projection Bleb Colocalized With F-Actin In Bleb Protrusions |
Alternative Antibody Names | Anti-Formin-Like Protein 1 antibody Anti-Cll-Associated Antigen Kw-13 antibody Anti-Leukocyte Formin antibody Anti-FMNL1 antibody Anti-C17orf1 antibody Anti-C17orf1B antibody Anti-FMNL antibody Anti-FRL1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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