產品詳情
簡單介紹:
Anti-FMO3 antibody (101-150 aa) (STJ96818)
詳情介紹:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Flavin-containing monooxygenase 3 (101-150 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC-P 1:100-1:300 ELISA 1:20000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FMO3 |
Gene ID: | 2328 |
Uniprot ID: | FMO3_HUMAN |
Immunogen Region: | 101-150 aa |
Specificity: | FMO3 Polyclonal Antibody detects endogenous levels of FMO3 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human FMO3 at the amino acid range 101-150 |
Function | Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation. |
Protein Name | Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3 Dimethylaniline Oxidase 3 Fmo Ii Fmo Form 2 Hepatic Flavin-Containing Monooxygenase 3 Fmo 3 Trimethylamine Monooxygenase |
Database Links | Reactome: R-HSA-217271 Reactome: R-HSA-5579019 |
Cellular Localisation | Microsome Membrane Single-Pass Membrane Protein Endoplasmic Reticulum Membrane |
Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 3 antibody Anti-Dimethylaniline Monooxygenase N-Oxide-Forming 3 antibody Anti-Dimethylaniline Oxidase 3 antibody Anti-Fmo Ii antibody Anti-Fmo Form 2 antibody Anti-Hepatic Flavin-Containing Monooxygenase 3 antibody Anti-Fmo 3 antibody Anti-Trimethylamine Monooxygenase antibody Anti-FMO3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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